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The evidence is even stronger here: Coffee drinkers have a 32-60% lower risk of Parkinsons disease The more coffee consumed, the greater the protective effect Caffeine specifically appears responsible for this benefit Protective mechanisms : Caffeine blocks adenosine receptors that can contribute to brain cell death Antioxidants reduce oxidative stress and inflammation in the brain Coffee increases brain-derived neurotrophic factor (BDNF), which supports neuron health May help clear beta-amyloid plaques associated with Alzheimers Long-term brain health : Starting coffee consumption in middle age appears to provide the greatest protective benefits for brain health in later years

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